S-100 and NSE as Serum Markers in Melanoma
نویسندگان
چکیده
منابع مشابه
Serum markers of cutaneous melanoma.
Malignant melanoma currently accounts for approximately 1%, of all cancer deaths. The incidence of cutaneous melanoma is rising worldwide. The treatment of early-stage melanoma consists primarily of surgical removal of the tumour. The overall 5-years survival rate for malignant melanoma is 81%. Recently, many efforts have been made to analyse the potential significance and the possible relation...
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To the Editor: We read with interest the work of Missler et al1 and Büttner and colleagues2 and agree with both sets of researchers on the need for reliable, noninvasive markers of neuronal damage following acute stroke. Such markers may allow prognostication of future clinical outcome and may be useful in acute therapy trials as surrogate markers of efficacy. However, neither study cited our p...
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OBJECTIVE Studies have shown signs of brain damage caused by different mechanisms in cocaine users. The serum neuron specific enolase and S100B protein are considered specific biochemical markers of neuronal and glial cell injury. This study aimed at comparing blood levels of S100B and NSE in chronic cocaine users and in volunteers who did not use cocaine or other illicit drugs. METHOD Twenty...
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S100B is a protein with dose-dependent neurotrophic and neurotoxic effects. Whether S100B in psychotic disorder mirrors pathophysiological mechanisms (which elicit exacerbation of disease) or compensatory action is unclear, as is its validity as a proxy marker for brain status. Insight may be gained by examining associations between serum S100B and indices of grey (cortical thickness (CT)) and ...
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The incidence of cutaneous malignant melanoma (CMM) is increasing in the Western world, despite the implementation of prevention campaigns for several years. Early detection, targeted at-risk populations helps to identify patients with beginning melanoma lesions, but despite these efforts, many patients often young,present with thicker tumors (with a higher Breslow, over 1mm Breslow is a measur...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 1997
ISSN: 0284-186X,1651-226X
DOI: 10.3109/02841869709001351